[The possible mechanism of lung injury induced by severe acute respiratory syndrome coronavirus spike glycoprotein].
Identifieur interne : 003C06 ( Main/Exploration ); précédent : 003C05; suivant : 003C07[The possible mechanism of lung injury induced by severe acute respiratory syndrome coronavirus spike glycoprotein].
Auteurs : Xin-Yan Yang [République populaire de Chine] ; Guo-Hua Yao ; Jun Xu ; Nan-Shan ZhongSource :
- Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases [ 1001-0939 ] ; 2006.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Cellules cultivées, Cellules endothéliales (métabolisme), Chimiokine CXCL10 (métabolisme), Femelle, Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (métabolisme), Humains, Interféron gamma (pharmacologie), Lésion pulmonaire (étiologie), Mâle, Protéines de l'enveloppe virale (métabolisme), Syndrome respiratoire aigu sévère (métabolisme), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS.
- MESH :
- métabolisme : Cellules endothéliales, Chimiokine CXCL10, Glycoprotéines membranaires, Protéines de l'enveloppe virale, Syndrome respiratoire aigu sévère.
- pharmacologie : Interféron gamma.
- virologie : Syndrome respiratoire aigu sévère.
- étiologie : Lésion pulmonaire.
- Adulte, Adulte d'âge moyen, Cellules cultivées, Femelle, Glycoprotéine de spicule des coronavirus, Humains, Mâle, Virus du SRAS.
English descriptors
- KwdEn :
- Adult, Cells, Cultured, Chemokine CXCL10 (metabolism), Endothelial Cells (metabolism), Female, Humans, Interferon-gamma (pharmacology), Lung Injury (etiology), Male, Membrane Glycoproteins (metabolism), Middle Aged, SARS Virus, Severe Acute Respiratory Syndrome (metabolism), Severe Acute Respiratory Syndrome (virology), Spike Glycoprotein, Coronavirus, Viral Envelope Proteins (metabolism).
- MESH :
- chemical , metabolism : Chemokine CXCL10, Membrane Glycoproteins, Viral Envelope Proteins.
- etiology : Lung Injury.
- metabolism : Endothelial Cells, Severe Acute Respiratory Syndrome.
- chemical , pharmacology : Interferon-gamma.
- virology : Severe Acute Respiratory Syndrome.
- Adult, Cells, Cultured, Female, Humans, Male, Middle Aged, SARS Virus, Spike Glycoprotein, Coronavirus.
Abstract
To investigate the role of severe acute respiratory syndrome coronavirus (SARS-CoV) in the induction of acute lung injury by promoting the synthesis of chemokine/cytokines in human endothelial cells.
PubMed: 17129463
Affiliations:
Links toward previous steps (curation, corpus...)
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- to stream PubMed, to step Curation: 001F78
- to stream PubMed, to step Checkpoint: 001E96
- to stream Ncbi, to step Merge: 001776
- to stream Ncbi, to step Curation: 001776
- to stream Ncbi, to step Checkpoint: 001776
- to stream Main, to step Merge: 003D64
- to stream Main, to step Curation: 003C06
Le document en format XML
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<author><name sortKey="Yang, Xin Yan" sort="Yang, Xin Yan" uniqKey="Yang X" first="Xin-Yan" last="Yang">Xin-Yan Yang</name>
<affiliation wicri:level="1"><nlm:affiliation>Guangzhou Institute of Respiratory Disease, First Hospital Affiliated, Guangzhou Medical College, Guangzhou 510120, China.</nlm:affiliation>
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<wicri:regionArea>Guangzhou Institute of Respiratory Disease, First Hospital Affiliated, Guangzhou Medical College, Guangzhou 510120</wicri:regionArea>
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<author><name sortKey="Yao, Guo Hua" sort="Yao, Guo Hua" uniqKey="Yao G" first="Guo-Hua" last="Yao">Guo-Hua Yao</name>
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<author><name sortKey="Xu, Jun" sort="Xu, Jun" uniqKey="Xu J" first="Jun" last="Xu">Jun Xu</name>
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<author><name sortKey="Zhong, Nan Shan" sort="Zhong, Nan Shan" uniqKey="Zhong N" first="Nan-Shan" last="Zhong">Nan-Shan Zhong</name>
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<author><name sortKey="Xu, Jun" sort="Xu, Jun" uniqKey="Xu J" first="Jun" last="Xu">Jun Xu</name>
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<series><title level="j">Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases</title>
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<term>Cells, Cultured</term>
<term>Chemokine CXCL10 (metabolism)</term>
<term>Endothelial Cells (metabolism)</term>
<term>Female</term>
<term>Humans</term>
<term>Interferon-gamma (pharmacology)</term>
<term>Lung Injury (etiology)</term>
<term>Male</term>
<term>Membrane Glycoproteins (metabolism)</term>
<term>Middle Aged</term>
<term>SARS Virus</term>
<term>Severe Acute Respiratory Syndrome (metabolism)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Viral Envelope Proteins (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Cellules cultivées</term>
<term>Cellules endothéliales (métabolisme)</term>
<term>Chimiokine CXCL10 (métabolisme)</term>
<term>Femelle</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Glycoprotéines membranaires (métabolisme)</term>
<term>Humains</term>
<term>Interféron gamma (pharmacologie)</term>
<term>Lésion pulmonaire (étiologie)</term>
<term>Mâle</term>
<term>Protéines de l'enveloppe virale (métabolisme)</term>
<term>Syndrome respiratoire aigu sévère (métabolisme)</term>
<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Virus du SRAS</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Chemokine CXCL10</term>
<term>Membrane Glycoproteins</term>
<term>Viral Envelope Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lung Injury</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Endothelial Cells</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cellules endothéliales</term>
<term>Chimiokine CXCL10</term>
<term>Glycoprotéines membranaires</term>
<term>Protéines de l'enveloppe virale</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Interféron gamma</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Interferon-gamma</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lésion pulmonaire</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Cells, Cultured</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>SARS Virus</term>
<term>Spike Glycoprotein, Coronavirus</term>
</keywords>
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<term>Adulte d'âge moyen</term>
<term>Cellules cultivées</term>
<term>Femelle</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Humains</term>
<term>Mâle</term>
<term>Virus du SRAS</term>
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<front><div type="abstract" xml:lang="en">To investigate the role of severe acute respiratory syndrome coronavirus (SARS-CoV) in the induction of acute lung injury by promoting the synthesis of chemokine/cytokines in human endothelial cells.</div>
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<name sortKey="Zhong, Nan Shan" sort="Zhong, Nan Shan" uniqKey="Zhong N" first="Nan-Shan" last="Zhong">Nan-Shan Zhong</name>
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<country name="République populaire de Chine"><region name="Guangdong"><name sortKey="Yang, Xin Yan" sort="Yang, Xin Yan" uniqKey="Yang X" first="Xin-Yan" last="Yang">Xin-Yan Yang</name>
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